Piotr Bałczewski has held the title of professor in organic chemistry since 2008. His undergraduate study was at the Technical University of Łódź and the Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences (CMMS PAS) in Łódź; PhD studies at the PAS Institute of Organic Chemistry, in Warsaw and CMMS PAS in Łódź; post-doctoral studies (2 years) with Prof. J.A. Joule in heterocyclic chemistry (marine alkaloids synthesis) at the University of Manchester; scientific visits in Universities of Milan, Rome, Negev, Barcelona; Zentral Institut für Organische Chemie in Berlin (2x); National Research Center, Cairo; Laboratoire de Chimie de Coordination LCC, CNRS, Toulouse. As an academic teacher and researcher, he has promoted many diplomas, MSc and PhD theses; he currently leads two research groups at CMMS PAS in Łódź (Functional Materials Synthesis Group) and at the Jan Długosz University of Częstochowa (Structural and Material Chemistry Group). First vice-president of the Polish Chemical Society (2018-2010, 2003-2001). He has participated in many domestic and international scientific and editorial boards and journal-owner boards (Chemistry Europe - European Chemical Societies Publishing Journals, ABC, PCCP). Honored with many domestic and international distinctions, among which the most important are: The Hanuš Medal (Brno, 2002) (http://www.csch.cz/o-spolecnosti/oceneni/hanusova-medaile/) and The Chemistry Europe Fellow 2016/2017 (Liverpool – 2018 (https://chemistry-europe.onlinelibrary.wiley.com/hub/fellows).
Organic/heteroorganic chemistry at the interface of materials, biology and medicine; new methodologies and techniques in organic synthesis (ultrasounds, mechanochemistry, microwaves, flow chemistry); total synthesis of biomolecules (cyclopentanoids, alkaloids, lignanoids, P, S, N-heteronium salts) including new solid state pharmaceutical formulations against COVID-19; material chemistry (organic materials for optoelectronics) including absorption and emission spectroscopy.
Bałczewski P. et al, (2017). “Ultrasound supported Bradsher reaction in aqueous and nonaqueous media: first use of ultrasounds in electrophilic aromatic cyclisation leading to polyacenes”, Ultrasonics Sonochemistry, 34, 743–753;
Bałczewski P. et al, (2019). “Ultrasound-assisted synthesis of RO- and RS-substituted (hetero)acenes via oxo- and thio-Friedel-Crafts/Bradsher reactions”, Ultrasonics. Sonochemistry, 58, 104640;
Bałczewski P. et al, (2019). “Mono-aryl/alkylthio-substituted (Hetero)acenes of Exceptional Thermal and Photochemical Stability via Thio-Friedel Crafts/Bradsher Cyclization Reaction”, Chem. Eur. J. 25, 14148–14161;
Bałczewski P. et al, (2020). “Ecotoxicity of ammonium chlorophenoxyacetate derivatives towards aquatic organisms: Unexpected enhanced toxicity upon oxygen by sulfur replaceme”, J.Haz.Mat., 382, 121086;
Turek M., Bałczewski P. et al, (2020). “Modification of the Microtox® Basic Solid Phase Test: a New Application for the Ecotoxicological Studies on Poorly Soluble Antihypertensive Drugs”, J.Haz.Mat., 399, 122839.
Teresa Basinska has been an associate professor at CMMS PAS since 2017. She holds a master’s degree in pharmacy from the Medical Academy in (Lodz) and earned her PhD in chemistry in 1996 at CMMS PAS (supervised by Prof. S. Slomkowski). Afterwards in 1996-1998 she spent post-doctoral fellowship at the University of Utah, Salt Lake City (USA) in the Department of Bioengineering under supervision of Prof. Karin Caldwell. She then returned to CMMS PAS, where she currently works. In 1998-2018 she was a principal investigator for 8 research projects sponsored by the Polish Ministry of Science and Higher Education. Currently, she leads a colloid group involved in two research projects funded by the National Centre of Science (in Poland). She is a co-organizer of the triennial Young European Scientists Workshops, organized under the auspices of the European Polymer Federation. During 2010-2020 she was involved in international research projects and was collaboration leader from the Polish side, together with Prof. MM. Chehimi (2) and Dr. C. Mangeney (1) at the University of Paris VII (Denise Diderot), France (Polonium projects) and Dr. D-F. Anghel at the Institute of Physical Chemistry of Romanian Academy in Bucharest (Romania), under the framework of the exchange program between Academies.
She is the author or coauthor of over 60 scientific articles and 3 book chapters. She has presented research findings at over 50 scientific conferences in Poland and abroad in the form of invited or plenary lectures and oral communications.
Polymer particles for biomedical applications, diagnostic tests and controlled drug delivery systems; polymer particles with shape anisotropy; interactions of polymer particles with proteins and biological tissues; arrangements of colloidal particles on solid supports.
Basinska T. (2005). “Hydrophilic core-shell microspheres: a suitable support for controlled attachment of proteins and biomedical diagnostics”, Macromol. Biosci., 5, 1145-1168.
Griffete N., Dybkowska M., Glebocki B., Basinska T., Connan C., Maître A., Chehimi M.M., Slomkowski S., Mangeney C. (2010). “Thermoresponsive colloidal crystals built from core-shell poly(styrene/α-tert-butoxy-ω-vinylbenzylpolyglycidol) microspheres”, Langmuir, 26, 11550–11557.
Basinska T., Slomkowski S. (2012). “Design of polyglycidol-containing microspheres for biomedical applications”, Chemical Papers, 66, 352-368.
Gosecka M., Basinska T., Slomkowski S., Tracz A., Chehimi M.M. (2014). „Mechanism of particle formation in radical emulsion copolymerization of styrene with a-tert-butoxy-ω-vinylbenzyl-polyglycidol macromonomer”, Polymer, 55, 788-797.
Komar P., Gosecka M., Gadzinowski M., Gosecki M., Makowski T., Slomkowski S., Basinska T.(2018). „Core-shell spheroidal microparticles with polystyrene cores and rich in polyglycidol shells”, Polymer, 146, 6-11.
Malgorzata Basko has been an adjunct at the Polymer Division (formerly the Department of Polymer Chemistry), Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences (CMMS PAS) in Łódź since 2008. She received her PhD from CMMS PAS in 2003. Afterwards she spent a postdoctoral fellowship at Ghent University (Belgium, Prof. Filip Du Prez’s research group – 11 months) and at Leuven University (Belgium, Prof. Ivo Vankelecom’s research group – 7 months). Her stay abroad initiated Polish-Belgian cooperation which has continued for years under bilateral research programs and resulted in several joint publications. Her research interests encompass the synthesis of biocompatible and biodegradable polymers for application in different areas, including biomedicine and filtration.
Polymer chemistry, biodegradable polymers, networks, hydrogels, composites.
Socka M., Michalski A., Pelin I.M., Pawlak A., Tanasa F., Biela T., Basko M.* (2020). “Preparation of biomimetic composites of hydroxyapatite and star-shaped poly(2,2-dimethyl trimethylene carbonate)s terminated with carboxyl end-groups”, Polymer 186 122078.
Danko M., Basko M.*, Ďurkáčová S., Duda A., Mosnáček J.* (2018). “Functional polyesters with pendant double bonds prepared by coordination−insertion and cationic ring-opening copolymerizations of ε‑caprolactone with renewable tulipalin A”, Macromolecules 51, 3582−3596.
Basko M., Bednarek M., Vlaminck L., Kubisa P., Du Prez F. E. (2017). “Biodegradable polymer networks via triazolinedione-crosslinking of oleyl-functionalized poly(ε-caprolactone)”, European Polymer Journal, 89, 230–240.
Baśko M., Kubisa P. (2007). “Polyester oligodiols by cationic AM copolymerization of lactide and caprolactone initiated by diols”, J. Polym Sci Pol Chem 45 (5): 3090-3097.
Marek Brzeziński invstigates the properties and applications of supramolecular materials based on biocompatible polymers. During a Humboldt fellowship at Freie Universität Berlin and Helmholtz-Zentrum Berlin for Materials and Energy, he worked on a project involving the use of microfluidics to design supramolecular capsules for drug delivery. Currently, he is an assistant professor at the Centre of Molecular and Macromolecular Studies (CMMS PAS) in Lodz and his current research interests include functional polymer design and micro- and nano-particles for biomedical applications.
Supramolecular polymers, drug delivery systems, micro- and nano-particles.
Brzeziński M., Biela T. (2015). “Supramolecular polylactides by the cooperative interaction of the end groups and stereocomplexation”, Macromolecules, 48, 2994–3004.
Brzeziński M., Kacprzak A., Calderón M., Seiffert S. (2017). “Metallo-polymer chain extension controls the morphology and release kinetics of microparticles composed of terpyridine-capped polylactides and their stereocomplexes, Macromol”, Rapid Comunn., 38 (7), 1600790.
Brzeziński M., Wedepohl S., Kost B., Calderón M. (2018). “Nanoparticles from supramolecular polylactides overcome drug resistance of cancer cells”, Eur. Polym. J., 109, 117-123.
Brzeziński M., Kost B., Wedepohl S., Socka M., Biela T., Calderón M. (2019). “Stereocomplexed PLA microspheres: Control over morphology, drug encapsulation and anticancer activity”, Colloid Surface B, 184, 11054.
Arkadiusz Chworos is an associate professor in the fields of chemistry/biochemistry and biomaterial sciences at the Centre of Molecular and Macromolecular Studies PAS (CBMM PAS) in Łódź. He earned his PhD in bioorganic chemistry in 2001. After a short postdoc at Laboratoire de Chimie de Coordination du CNRS, Toulouse with Prof. Bernard Meunier he moved to the University of California Santa Barbara where he was associated as a postdoctoral fellow with Prof. Luc Jaeger and then as an independent Project Scientist. In 2011 he moved back to CBMM PAS, where he is now a group leader and since 2016 Deputy Director for Science.
Structural and functional RNA nano-objects, gene expression regulation, RNA-protein interactions, conjugated oligoelectrolytes, biomaterials.
Graczyk A., Pawlowska R., Jedrzejczyk D., Chworos A. (2020). “Gold Nanoparticles in Conjunction with Nucleic Acids as a Modern Molecular System for Cellular Delivery”, Molecules, 25, 204, 1-27.
Jedrzejczyk D., Chworos A. (2019). “RNA Trimeric Nanoparticle for Gene Expression Regulating in a Model GFP System”, ACS Synthetic Biology, 8(3), 491-497.
Suwara J., Lukasik B., Zurawinski R., Pawlowska R., Chworos A. (2020). “Highly Fluorescent Distyrylnaphthalene Derivatives as a Tool for Visualization of Cellular Membranes”, Materials, 13(4), 951, 1-20.
Geary C., Chworos A., Verzemnieks E., Voss N. R., Jaeger L. (2017). “Composing RNA nanostructures from a syntax of RNA structural modules” , Nano Letters, 17 (11), 7095–7101.
Józef Drabowicz earned his MSc at the University of Lodz (1969). Since then he has been employed at the Centre of Molecular and Macromolecular Studies, Polish Academy of Science (CMMS PAS) in Lodz (since 1998 as professor). Since 2002 he has taught at the Jan Dlugosz University in Czestochowa. He earned his PhD in 1975 and DSc (habilitation) in 1987. He is co-author of more than 250 publications. At present he is the editor for Science of Synthesis – Knowledge Updates Vol. 39. and Vol. 33 and a member of the editorial boards several journals.
Chemistry and stereochemistry of heteroorganic compounds; synthetic methodologies; organic materials.
Marta Dudek graduated from the Faculty of Pharmacy at Warsaw Medical University in 2006. She earned her PhD from the same university in 2011, defending a thesis on solid-state NMR studies of bioactive triterpene xylosides isolated from natural sources. She completed two postdoctoral fellowships. The first one was a part of the FUGA fellowship granted to her by the Polish National Science Center, during which she worked in Prof. Marek Potrzebowski’s group, improving her skills in the application of advanced solid-state NMR experiments to solving structurally challenging problems. The second fellowship, awarded by the Polish Ministry of Science and Higher Education, took place in Prof. Graeme Day’s research group at the University of Southampton, UK, where she became familiar with crystal structure prediction (CSP) calculations. Since 2015 she has been working at the Center of Molecular and Macromolecular Studies, Polish Academy of Sciences (CMMS PAS), implementing CSP calculations and solid-state NMR studies in order to better understand the crystallization behavior of organic molecules.
Crystal structure prediction, solid-state NMR, understanding crystallization mechanisms, polymorphism and solvatomorphism, challenging cases of structure determination.
Dudek M. K., Jeziorna A., Potrzebowski M. J. (2016). “Computational and experimental study of reversible hydration/dehydration processes in molecular crystals of natural products – a case of catechin”, CrystEngComm , 18, 5267–5277.
Dudek M. K., Day G. M. (2019). “Explaining crystallization preferences of two polyphenolic diastereoisomers by crystal structure prediction”, CrystEngComm, 21, 2067–2079.
Dudek M. K. et al. (2019). “Understanding the formation of apremilast cocrystals”. Acta Cryst., B75, 803–814;
Dudek M. K., Paluch P., Pindelska E. (2020). “Crystal structures of two furazidin polymorphs revealed by a joint effort of crystal structure prediction and NMR crystallography”, Acta Cryst., B76, 322−335;
Dudek M. K., et al. (2020). “Crystal structure determination of an elusive methanol solvate - hydrate of catechin using crystal structure prediction and NMR crystallography”, CrystEngComm, https://doi.org/10.1039/D0CE00452A.
Markus Düchler has held the position of associate professor at the Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences (CBMM PAS) since 2013. He earned his PhD at the University of Vienna, followed by postdoctoral positions at the Ludwig Boltzmann Institute for Cytokine Research, AKH Vienna; Nofer Institute of Occupational Medicine, Łódź, Poland; and the Polish Mother’s Memorial Hospital – Research Institute, Łódź, Poland, among other institutions.
Cancer immunosuppression, extracellular vesicles.
Kluszczyńska K., Czernek L., Cypryk W., Pęczek Ł., Düchler M. (2019). “Methods for the determination of the purity of exosomes”, Curr Pharm Des., 25(42): 4464-4485.
Düchler M., Czernek L., Peczek L., Cypryk W., Sztiller-Sikorska M., Czyz M. (2019). “Melanoma-Derived Extracellular Vesicles Bear the Potential for the Induction of Antigen-Specific Tolerance” CELLS 2019; 8 (7): E665.
Czernek L, Düchler M. (2017). “Functions of Cancer-Derived Extracellular Vesicles in Immunosuppression”, Arch Immunol Ther Exp, 65(4): 311-323.
Czernek L., Chworos A., Düchler M. (2015). “The Uptake of Extracellular Vesicles is Affected by the Differentiation Status of Myeloid Cells”, Scand J Immunol., 82(6): 506-14.
Piotr Kaszyński is a professor of chemistry at the Centre of Molecular and Macromolecular Studies of Polish Academy of Sciences (PAS) and University of Lodz (UL) in Lodz, Poland. He received his PhD degree in organic chemistry in 1991 (University of Texas at Austin), and his DSc (habilitation) in 2007 (University of Lodz). He spent two years at Caltech as a postdoctoral fellow working in the area of organic magnetic materials, before joining Vanderbilt University in Nashville, TN, USA in 1993. In 2015 he moved the bulk of his research program to the Polish Academy of Sciences and the University of Lodz, while maintaining ties with Middle Tennessee State University in the United States. He is the author or co-author of 185 peer-reviewed publications.
Chemistry of boron clusters and stable radicals; functional materials; liquid crystals; materials for electrooptical, molecular electronics, photovoltaic and spintronic investigation.
Jasiński M., Szczytko J., Pociecha D., Monobe H., Kaszyński, P. (2016). “Substituent-dependent magnetic behavior of discotic benzo[e][1,2,4]triazinyls”, J. Am. Chem. Soc., 138, 9421−9424.
Kaszyński, P. Constantinides C. P., Young V. G. Jr., (2016). “The Planar Blatter Radical: structural chemistry of 1,4-dihydrobenzo[e][1,2,4]triazin-4-yls”, Angew. Chem. Int. Ed., 55, 11149-11152.
Ali M. O., Lasseter J. C., Żurawiński R., Pietrzak A., Pecyna J., Wojciechowski J., Friedli A. C., Pociecha D., Kaszyński, P. (2019). “Thermal and photophysical properties of highly quadrupolar liquid crystalline derivatives of the [closo-B12H12]2- anion”, Chem. Eur. J., 25, 2616−2630.
Shivakumar K. I., Pociecha D., Szczytko J., Kapuściński S., Monobe H., Kaszyński P., (2020). “Photoconductive bent-core liquid crystalline radicals with a paramagnetic polar switchable phase”, J. Mater. Chem. C, 8, 1083−1088.
Bartos P., Young V. G. Jr., Kaszynski P. (2020). “Ring-fused 1,4-dihydro[1,2,4]triazin-4-yls through photocyclization” Org. Lett. , 22, 3835−3840.
Piotr Kiełbasiński is a professor of chemistry at the Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences (CMMS PAS). He received his PhD degree in Chemistry in 1977 and his DSc (habilitation) in 2000 (both at CMMS PAS). He spent 15 months at Nijmegen, the Netherlands as a postdoctoral fellow working in the area of sulfine chemistry (1977-1978). Then he returned to the CMMS PAS, where he has been employed to the present day. He received the title of Professor in 2009. He is the author or co-author of 136 peer-reviewed publications, including book chapters and one book.
Chemistry and stereochemistry of heteroorganic compounds, organic synthesis, application of enzymes in synthesis.
Rachwalski M., Wujkowska Z., Leśniak S., Kiełbasiński P. (2015). “Highly efficient asymmetric aziridination of unsaturated aldehydes promoted by chiral heteroorganic catalysts”, ChemCatChem, 7, 3589-3592.
Cierpiał T., Łuczak J., Kwiatkowska M., Kiełbasiński P., Śliwka L., Wiktorska K., Chilmonczyk Z., Milczarek M., Karwowska K. (2016). “New organofluorine isoselenocyanate analogs of sulforaphane: synthesis and anticancer activity”, ChemMedChem, 11, 2398−2409.
Otocka S., Kwiatkowska M., Madalińska L., Kiełbasiński P. (2017). “Chiral Organosulfur Ligands/Catalysts with a Stereogenic Sulfur Atom: Applications in Asymmetric Synthesis”, Chem. Rev., 117, 4147−4181.
Janicki I., Kiełbasiński P., Turrini N., Faber K., Hall M. (2017). “Asymmetric bioreduction of β-activated vinylphosphonate derivatives using ene-reductases”, Adv. Synth. Catal., 359, 4190−4196.
Cierpiał T., Kiełbasiński P, Kwiatkowska M., Łyżwa P., Lubelska K., Kuran D., Dąbrowska A., Kruszewska H., Chilmonczyk Z., Wiktorska K. (2020). “Fluoroaryl analogs of sulforaphane – a group of compounds of anticancer and antimicrobial activity”, Bioorg. Chem., 94, Article No. 103 454.
Janicki I., Łyżwa P., Kiełbasiński P. (2020). “The first enzyme-promoted addition of nitromethane to imines (aza-Henry reaction)” Bioorg. Chem., 94, Article No. 103 377. Bioorg. Chem., 96, Article No. 103 548.
Błaszczyk J., Kiełbasiński P., (2020). “Quarter of a century after: a glimpse at the conformation and mechanism of Candida antarctica Lipase B" Crystals, 10, art. No. 404.
Anna Kowalewska has been an associate professor at the Center of Molecular and Macromolecular Studies, Polish Academy of Sciences (CMMS PAS) since 2015. She earned her PhD in chemistry (thesis on synthesis and reactivity of sterically hindered organosilicon compounds) from CMMS PAS in 1998. Afterwards she spent an 18-month postdoctoral fellowship at Laboratoire de Recherche sur les Polymères CNRS – Université PARIS XII (1998–1999) working on photocrosslinkable silicones. She returned to CMMS PAS in Lodz and began an academic career as an assistant professor working with organosilicon materials. In 2010 she obtained her DSc (habilitation) in polymer chemistry (focussed on application of sterically hindered carbosilanes in polymer chemstry). In 2013 she become the leader of the Hybrid Materials Physicochemistry Research Group (Department of Engineering of Polymer Materials at CMMS PAS). Kowalewska is the author/co-author of 54 research papers, 4 reviews, 2 book chapters and 6 patents/3 patent applications.
Hybrid materials, linear polysilsesquioxanes, POSS, supramolecular chemistry.
Kowalewska A. et al (2015). “Synthesis of ladder silsesquioxanes by in situ polycondensation of cyclic tetravinylsiloxanetetraols”, Silicon 7, 133.
Kowalewska A. (2015). “Supramolecular Self-Assembly of Linear Oligosilsesquioxanes on Mica – AFM Surface Imaging and Hydrophilicity Studies”, Soft Matter 11 , 4818.
Kowalewska A. (2017). “Solid-state dynamics and single-crystal to single-crystal structural transformations in octakis(3-chloropropyl)octasilsesquioxane and octavinyloctasilsesquioxane”, PhysChemChemPhys 19 , 27516.
Kowalewska A. (2019). “Hybrid polysilsesquioxanes for fluorescence resonance energy transfer”, Dyes and Pigments 170, 107622.
Kowalewska A. (2020). “Thiol-ene addition of mercaptoalcohols to poly(vinylsiloxanes) under visible light photocatalysis – An approach towards cross-linkable hydrophilic silicones”, Polyhedron 185, 114588.
Prof. Marek Potrzebowski is the Director (CEO) of the Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences (CMMS PAS), where he also leads the Environmental Laboratory of Physicochemical Research of Organic Compounds and Polymers and is head of the Division of Structural Studies. He is also a Corresponding Member of the Polish Academy of Sciences.
Solid-state reactions and structural chemistry – understanding mechanochemical reactions in a ball mill; development of silica-based drug delivery systems and understanding the mechanism of encapsulating Active Pharmaceutical Ingredients (APIs) and organic compounds inside the mesopores of silica nanoparticles; understanding crystallization processes and preferences of organic compounds to form polymorphs, cocrystals, solvates and hydrates; structural characterization of organic molecules in a condensed matter using solid-state NMR, powder X-Ray diffraction, single crystal X-Ray diffraction; developing Solid State NMR methodologies using Very Fast Magic Angle Spinning.
Kobayashi S., Mao K., Paluch P., Nowak-Król A., Śniechowska J., Nishiyama Y., Gryko D. T., Potrzebowski M. J., Pruski M. (2013). “Study of Intermolecular Interactions in the Corrole Matrix by Solid-State NMR under 100 kHz MAS and Theoretical Calculations”, Angew Chem Int Ed Engl.
Paluch P., Pawlak T., Amoureux J.-P., and Potrzebowski M. J. (2013). “Simple and accurate determination of X-H distances under ultra-fast MAS NMR”, J Magn Reson.
Pawlak T., Jaworska M., Potrzebowski M. J., (2013). “NMR crystallography of alpha-poly(L-lactide)”, Physical Chemistry Chemical Physics.
Dudek M.K., Wielgus E., Paluch P., Śniechowska J., Kostrzewa M., Day G. M., Bujacz G. D., Potrzebowski M. J. (2019). “Understanding the formation of apremilast cocrystals”, Acta Cryst.
Jedrzejewska H., Wielgus E., Kazmierski S., Rogala H., Wierzbicki M., Wroblewska A., Pawlak T., Potrzebowski M. J., Szumna A. (2020). “Porous Molecular Capsules as Non-Polymeric Transducers of Mechanical Forces to Mechanophores”, Chem. Eur. J.