Maj Institute of Pharmacology, PASJerzy Haber Institute of Catalysis and Surface Chemistry, PAS
Development of functional theranostic nanoparticles and its evaluation in various cellular models of Parkinson's disorders.
Neuroprotective properties of theranostic lanthanide oxide nanoparticles against neurotoxin-induced cellular models of Parkinson’s disease Life Sciences
phone no. +48 575 190 862
rugmanim@if-pan.krakow.pl
Need for multifunctional neuroprotective agent for Parkinson's disease and its early detection and therapy using imaging contrast agents.
The proposal relies on the development of multifunctional cerium oxide neuroprotective nanoparticles with co-substitution strategy imparting both fluorescence and MR contrast features, thus, providing a powerful tool for neuroprotection and diagnosis of PD.
Rugmani Meenambal earned her Ph.D. from Pondicherry University, India, on the thesis "Synthesis and structural insights of Ln3+ doped β-Ca3(PO4)2 and LnPO4 contrast agents for multimodal imaging applications" in 2018. She was employed at the Department of Science and Technology funded INSPIRE project at NIMHANS during 2018-2022. Currently, she is working under the PASIFIC Programme at the Institute of Pharmacology of the PAS.
Meenambal, R., & Bharath, M. S. (2020). Nanocarriers for effective nutraceutical delivery to the brain. Neurochemistry International, 140, 104851.
Meenambal, R., Poojar, P., Geethanath, S., Anitha, T. S., & Kannan, S. (2019). Lanthanide phosphate (LnPO4) rods as bio‐probes: A systematic investigation on structural, optical, magnetic, and biological characteristics. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 107(5), 1372-1383.
Meenambal, R., & Kannan, S. (2018). Design and structural investigations of Yb3+ substituted β-Ca3 (PO4) 2 contrast agents for bimodal NIR luminescence and X-ray CT imaging. Materials Science and Engineering: C, 91, 817-823.
12 Smętna, 31-343 Kraków, Poland
Supervisor
Danuta Jantas, PhD
8 Niezapominajek, 30-239 Kraków, Poland
Prof. Piotr Warszyński
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